Reply to “Silent Progression or Bout Onset Progressive Multiple Sclerosis?”
نویسندگان
چکیده
منابع مشابه
Multiple sclerosis that is progressive from the time of onset: clinical characteristics and progression of disability.
OBJECTIVE To use the new consensus definitions of primary progressive multiple sclerosis (PPMS) and progressive relapsing multiple sclerosis (PRMS) to report the demographic, clinical, and natural history characteristics of multiple sclerosis (MS) that is progressive from the time of onset. DESIGN Retrospective study by database/chart review and telephone interview. SETTING Multiple scleros...
متن کاملBeta‐interferon exposure and onset of secondary progressive multiple sclerosis
BACKGROUND AND PURPOSE Beta-interferons (IFNβ) are the most widely prescribed drugs for patients with multiple sclerosis (MS). However, whether or not treatment with IFNβ can delay secondary progressive MS (SPMS) onset remains unknown. Our aim was to examine the association between IFNβ exposure and SPMS onset in patients with relapsing-remitting MS (RRMS). METHODS A retrospective cohort stud...
متن کاملPrimary-progressive multiple sclerosis.
About 10-15% of patients with multiple sclerosis (MS) present with gradually increasing neurological disability, a disorder known as primary-progressive multiple sclerosis (PPMS). Compared with relapse-onset multiple sclerosis, people with PPMS are older at onset and a higher proportion are men. Inflammatory white-matter lesions are less evident but diffuse axonal loss and microglial activation...
متن کاملOral and Laryngeal Diadochokinetic Rate in Multiple Sclerosis: Relationship to Disease Progression
Background: The first purpose of this study was to investigate the rate of oral and laryngeal Diadochokinesis (DDK) in Multiple Sclerosis (MS) patients in comparison with healthy people. The second goal was to determine if DDK rate has any relationship with the disease progression. Methods: In this cross-sectional study, two groups were enroll...
متن کاملEarly onset multiple sclerosis
Objective: To evaluate the clinical course of MS in individuals with onset of MS before age 16. Methods: Patients with onset of MS before age 16 (n 116) with complete clinical information on the clinical course from the MS Clinic at The University of British Columbia (UBC) Site Hospital computerized database (MS-COSTAR) were included in this study. The data were compared to those from the Canad...
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ژورنال
عنوان ژورنال: Annals of Neurology
سال: 2019
ISSN: 0364-5134,1531-8249
DOI: 10.1002/ana.25536